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Glucagon-like peptide-1 receptor agonists and risk for depression in older adults with type 2 diabetes: a target trial emulation study
Its longevity in the market gives it a strong record of safety, with consistent data on heart health benefits for people with type 2 diabetes
Longer-acting GLP-1 analogs that can be administered once each month are currently in clinical trials
Trp-CA has been identified as an endogenous ligand of the orphan G protein-coupled receptor MRGPRE, and its activation promotes GLP-1 secretion through both Gs-cAMP and -arrestin-1-ALDOA signaling pathways, thereby improving glucose tolerance in diabetic mice
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